GHK-Cu research peptide
Skin & Hair

GHK-Cu

Copper-bound tripeptide (Gly-His-Lys) studied for skin remodelling, hair-follicle activity and ECM signalling.

Purity

99%+

CAS Number

89030-95-5

Status

Made to Order

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Same-Day (before 2pm)

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£199.99

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Research verification required. All orders are reviewed before dispatch. You will receive an email confirmation and a WhatsApp or phone call within 60 minutes to verify your research purpose.

Third-Party CoA Included Free Delivery Over £75 Research Use Only

About GHK-Cu

GHK-Cu is the copper(II) complex of the naturally occurring tripeptide glycyl-L-histidyl-L-lysine. It has been extensively investigated for its role in extracellular-matrix remodelling, fibroblast signalling and dermal repair pathways. Researchers study GHK-Cu in models of skin ageing, wound healing, hair-follicle biology and copper-dependent gene expression.

Research Applications

Research Mechanism — GHK-Cu

A simplified summary of what GHK-Cu is studied for in research models. For laboratory in-vitro use only.

Sequence:Gly-His-Lys (complexed with Cu²⁺)

Origin: Naturally occurring human copper-binding tripeptide, synthesised as a Cu²⁺-chelated complex for laboratory research.

  1. Molecular target

    A copper-binding tripeptide investigated for its delivery of Cu²⁺ to intracellular enzymes and its interaction with extracellular matrix components in research models.

    • Lysyl oxidase (copper-dependent enzyme)
    • Superoxide dismutase 3 (SOD3) cofactor delivery
    • Decorin and glycosaminoglycan binding sites

  2. Investigated pathways

    Preclinical studies have explored downstream effects on antioxidant signalling, extracellular matrix remodelling, and gene-expression responses in cultured cells.

    • Collagen and elastin synthesis modulation
    • Nrf2 antioxidant-response element signalling
    • MMP-2 matrix metalloproteinase regulation

  3. Preclinical research applications

    Used as a research tool in laboratory models exploring dermal-fibroblast biology, oxidative-stress science, and matrix-remodelling research. Not approved for human use.

    • Dermal fibroblast and keratinocyte cultures
    • Hair-follicle dermal papilla cell models
    • In vitro skin-aging and oxidative-stress assays

For research use only. GHK-Cu is not approved as a medicine in the UK and is not intended for human or veterinary administration. See the compliance page for full terms.

Technical Specifications

Compound NameGHK-Cu
CategorySkin & Hair
CAS Number89030-95-5
Molecular Weight402.92 g/mol
Molecular FormulaC₁₄H₂₄CuN₆O₄
SequenceGly-His-Lys (with Cu²⁺ chelation)
Purity≥99%+ (HPLC)
FormLyophilised powder
StorageStore lyophilised at -20°C. Protect from light. Reconstituted: aliquot and store at -80°C. Use within 30 days of reconstitution.
ReconstitutionReconstitute in bacteriostatic or sterile water. Typical stock concentration: 2 mg/mL.

Certificate of Analysis

Every order of GHK-Cu includes a batch-specific CoA with HPLC chromatogram, mass spectrometry data, and laboratory accreditation details.

View Sample CoA

GHK-Cu — Frequently Asked Questions

What is GHK-Cu?

GHK-Cu is the copper(II) complex of the tripeptide glycyl-histidyl-lysine. It is studied in laboratory research for roles in extracellular-matrix signalling, dermal fibroblast behaviour and hair-follicle biology.

What purity is your GHK-Cu?

99%+, confirmed by independent third-party HPLC analysis. Batch-specific CoA included.

Is GHK-Cu approved for human use?

No. Supplied for in vitro laboratory research only. Not a licensed medicine.

📊Certificates of Analysis🔬Quality & Testing📋Research Guidelines⚖️UK Compliance

GHK-Cu is supplied by Premio Peptides (BELL RED LIMITED) exclusively for in vitro laboratory research. It is not a licensed medicine, is not approved for human or veterinary use, and must not be administered to any living organism outside a formally approved research protocol. Purchasers assume full responsibility for compliance with applicable regulations.

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