Glutathione research peptide
Anti-Ageing & Longevity

Glutathione

Reduced glutathione (GSH) tripeptide investigated for redox balance, antioxidant defence and detoxification research.

Purity

99%+

CAS Number

70-18-8

Status

Made to Order

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£199.99

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Research verification required. All orders are reviewed before dispatch. You will receive an email confirmation and a WhatsApp or phone call within 60 minutes to verify your research purpose.

Third-Party CoA Included Free Delivery Over £75 Research Use Only

About Glutathione

Glutathione (GSH) is a γ-glutamyl tripeptide and the most abundant intracellular thiol antioxidant, biosynthesised from glutamate, cysteine and glycine. It has been researched extensively for its association with cellular redox balance, glutathione peroxidase activity and Phase II xenobiotic detoxification pathways. Supplied as lyophilised reduced GSH for in vitro research only.

Research Applications

Research Mechanism — Glutathione

A simplified summary of what Glutathione is studied for in research models. For laboratory in-vitro use only.

Sequence:γ-Glu-Cys-Gly (GSH)

Origin: Endogenous tripeptide synthesised in the cytosol via γ-glutamylcysteine synthetase and glutathione synthetase.

  1. Molecular target

    Glutathione is investigated as the principal intracellular thiol redox buffer. Preclinical work has examined its role as a cofactor for selenium-dependent peroxidase enzymes.

    • Cofactor for glutathione peroxidase (GPx1-GPx4)
    • Substrate for glutathione S-transferases (GSTs)
    • Modulator of the Nrf2/Keap1 redox-sensing axis

  2. Investigated pathways

    Studies have explored GSH:GSSG ratio dynamics during oxidative challenge. Research has associated glutathione with thiol-disulfide exchange across multiple redox-sensitive proteins.

    • Reduction of hydrogen peroxide via the GPx cycle
    • Phase II xenobiotic conjugation through GST activity
    • S-glutathionylation of cysteine residues on signalling proteins

  3. Preclinical research applications

    Preclinical studies have explored glutathione in hepatocyte, neuronal and erythrocyte models of oxidative stress. Not approved for human use.

    • In vitro hepatocyte models of acetaminophen-induced stress
    • Cell-culture assays of mitochondrial ROS handling
    • Rodent models examining γ-glutamyl cycle turnover

For research use only. Glutathione is not approved as a medicine in the UK and is not intended for human or veterinary administration. See the compliance page for full terms.

Technical Specifications

Compound NameGlutathione
CategoryAnti-Ageing & Longevity
CAS Number70-18-8
Molecular Weight307.32 g/mol
Molecular FormulaC₁₀H₁₇N₃O₆S
SequenceTripeptide γ-L-Glutamyl-L-Cysteinyl-Glycine
Purity≥99%+ (HPLC)
FormLyophilised powder
StorageStore lyophilised at -20°C. Protect from light. Reconstituted: aliquot and store at -80°C. Use within 30 days of reconstitution.
ReconstitutionReconstitute in sterile or bacteriostatic water. Typical stock concentration: 30 mg/mL. Solution should be prepared fresh due to thiol oxidation.

Certificate of Analysis

Every order of Glutathione includes a batch-specific CoA with HPLC chromatogram, mass spectrometry data, and laboratory accreditation details.

View Sample CoA

Glutathione — Frequently Asked Questions

What is Glutathione?

Glutathione (GSH) is a reduced γ-glutamyl tripeptide studied in laboratory research for its association with cellular redox homeostasis, antioxidant defence enzymes and Phase II detoxification. It is supplied for in vitro research only.

What purity is your Glutathione?

99%+, confirmed by independent third-party HPLC analysis. Batch-specific CoA included.

Is Glutathione approved for human use?

No. Supplied for in vitro laboratory research only. Not a licensed medicine.

📊Certificates of Analysis🔬Quality & Testing📋Research Guidelines⚖️UK Compliance

Glutathione is supplied by Premio Peptides (BELL RED LIMITED) exclusively for in vitro laboratory research. It is not a licensed medicine, is not approved for human or veterinary use, and must not be administered to any living organism outside a formally approved research protocol. Purchasers assume full responsibility for compliance with applicable regulations.

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