NAD+ research peptide
Anti-Ageing & Longevity

NAD+

Pyridine nucleotide coenzyme researched for mitochondrial function, sirtuin signalling and cellular redox.

Purity

99%+

CAS Number

53-84-9

Status

Made to Order

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£199.99

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Research verification required. All orders are reviewed before dispatch. You will receive an email confirmation and a WhatsApp or phone call within 60 minutes to verify your research purpose.

Third-Party CoA Included Free Delivery Over £75 Research Use Only

About NAD+

Nicotinamide adenine dinucleotide (NAD+) is a ubiquitous pyridine nucleotide coenzyme central to redox biology and sirtuin/PARP enzyme signalling. Available in two size variants (500mg and 1000mg) for laboratory research, NAD+ has been investigated extensively for its association with mitochondrial bioenergetics, DNA-damage response and ageing-related metabolic pathways. Supplied lyophilised for in vitro research only.

Research Applications

Research Mechanism — NAD+

A simplified summary of what NAD+ is studied for in research models. For laboratory in-vitro use only.

Sequence:Pyridine nucleotide cofactor — not a peptide

Origin: Endogenous coenzyme synthesised from tryptophan or vitamin B3 precursors via the de novo, Preiss-Handler and salvage pathways.

  1. Molecular target

    NAD+ functions as an obligate cosubstrate for sirtuins, PARPs and CD38, cycling between oxidised (NAD+) and reduced (NADH) states. Cellular NAD+ pools decline with age in preclinical models.

    • SIRT1-7 deacetylase family (NAD+-dependent)
    • PARP1 and PARP2 DNA-damage response enzymes
    • CD38 ectoenzyme and SARM1 axonal NADase
  2. Investigated pathways

    Research examines NAD+ involvement in mitochondrial bioenergetics, redox balance and DNA repair signalling. Precursors such as NMN and NR are studied as biosynthetic inputs.

    • Mitochondrial electron transport and OXPHOS coupling
    • Sirtuin-mediated deacetylation of FOXO and PGC-1a
    • Salvage pathway flux via NAMPT enzymatic activity
  3. Preclinical research applications

    Investigated in rodent and cell-culture models of metabolic decline, mitochondrial dysfunction and senescence-related endpoints. Not approved for human use.

    • Cellular senescence and replicative ageing assays
    • Murine models of metabolic and mitochondrial stress
    • In vitro DNA-damage and oxidative stress endpoints

For research use only. NAD+ is not approved as a medicine in the UK and is not intended for human or veterinary administration. See the compliance page for full terms.

Technical Specifications

Compound NameNAD+
CategoryAnti-Ageing & Longevity
CAS Number53-84-9
Molecular Weight663.43 g/mol
Molecular FormulaC₂₁H₂₇N₇O₁₄P₂
SequencePyridine nucleotide cofactor — not a peptide
Purity≥99%+ (HPLC)
FormLyophilised powder
StorageStore lyophilised at -20°C. Protect from light. Reconstituted: aliquot and store at -80°C. Use within 30 days of reconstitution.
ReconstitutionReconstitute in sterile or bacteriostatic water. Typical stock concentration: 50 mg/mL. Available in 500mg and 1000mg vial sizes.

Certificate of Analysis

Every order of NAD+ includes a batch-specific CoA with HPLC chromatogram, mass spectrometry data, and laboratory accreditation details.

View Sample CoA

NAD+ — Frequently Asked Questions

What is NAD+?

NAD+ is a pyridine nucleotide coenzyme studied in laboratory research for its association with sirtuin signalling, mitochondrial bioenergetics, DNA-repair pathways and cellular redox balance. It is supplied for in vitro research only.

What purity is your NAD+?

99%+, confirmed by independent third-party HPLC analysis. Batch-specific CoA included.

Is NAD+ approved for human use?

No. Supplied for in vitro laboratory research only. Not a licensed medicine.

NAD+ is supplied by Premio Peptides (BELL RED LIMITED) exclusively for in vitro laboratory research. It is not a licensed medicine, is not approved for human or veterinary use, and must not be administered to any living organism outside a formally approved research protocol. Purchasers assume full responsibility for compliance with applicable regulations.

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